Description

2H-Pyran-2-Carboxaldehyde, Tetrahydro-6-Methoxy-, (2S-Trans)- (9Ci) is a chiral, heterocyclic aldehyde building block of significant synthetic utility. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the synthesis of pharmaceuticals and fine chemicals. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fragrance industries for applications requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of antiviral, antibacterial, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific chirality is crucial for biological activity.
• Fine Chemical Production: Serves as a building block for creating complex natural product analogs, flavors, and fragrances.
• Asymmetric Catalysis Research: Employed as a test substrate or ligand precursor in the development of new chiral catalysts and methodologies.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	2H-Pyran-2-Carboxaldehyde, Tetrahydro-6-Methoxy-, (2S-Trans)- (9Ci)
CAS No.	88595-34-0
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(2S-trans)-Tetrahydro-6-methoxy-2H-pyran-2-carboxaldehyde; (2S,6R)-6-Methoxytetrahydro-2H-pyran-2-carbaldehyde; 6-Methoxytetrahydro-2H-pyran-2-carboxaldehyde, (2S-trans)-; L-(+)-6-Methoxytetrahydro-2H-pyran-2-carboxaldehyde; (2S,6R)-6-Methoxy-2-tetrahydropyrancarboxaldehyde; Tetrahydro-6-methoxy-2H-pyran-2-carboxaldehyde, (2S-trans)-; (2S,6R)-6-Methoxy-tetrahydropyran-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our production of 2H-Pyran-2-Carboxaldehyde, Tetrahydro-6-Methoxy-, (2S-Trans)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized by advanced analytical techniques including chiral HPLC, GC, NMR, and optical rotation measurement. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and volatility. The container should be kept in a cool, dry, and well-ventilated area, away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.