Description

3'-o-Demethyl-3'-o-Acetyl-12-Deoxyerythromycin is a key semi-synthetic derivative and advanced intermediate in the synthesis of novel macrolide antibiotics. This compound is valued for its role in developing next-generation antibacterial agents with improved efficacy and reduced resistance profiles. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of specialized antibiotic APIs.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of novel erythromycin-derived antibiotics and other macrolide therapeutics.
• Antibacterial Research: Used as a building block in medicinal chemistry for structure-activity relationship (SAR) studies to combat bacterial resistance.
• Process Development: Serves as a standard or reference material for scaling up and optimizing API manufacturing processes.
• Fine Chemical Synthesis: Employed in custom synthesis projects to create specialized macrolide compounds for clinical evaluation.

Basic Information

Product Name	3'-o-Demethyl-3'-o-Acetyl-12-Deoxyerythromycin
CAS No.	88505-41-3
Molecular Formula	C36H65NO12
Molecular Weight	703.90 g/mol
Synonyms	12-Deoxyerythromycin B 3'-Acetate; 3'-O-Acetyl-3'-O-demethyl-12-deoxyerythromycin; 3'-O-Acetyl-3'-demethyl-12-deoxyerythromycin; 3'-O-Acetyl-3'-demethyl-12-deoxyerythromycin B; Erythromycin B, 3'-demethyl-3'-acetyl-12-deoxy-; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione
EINECS	Contact for details

Quality Control

Our 3'-o-Demethyl-3'-o-Acetyl-12-Deoxyerythromycin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.