Description

(3,4,5-Tribromo-1H-Pyrrole-2-Yl)(2-Hydroxy-5-Bromophenyl) Ketone is a high-purity, multi-brominated heterocyclic ketone compound that serves as a critical advanced intermediate in modern organic synthesis. Its unique molecular architecture, featuring both pyrrole and phenolic bromine substituents, makes it a valuable building block for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought by research institutions and chemical manufacturers specializing in pharmaceuticals, agrochemicals, and materials science for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing antimicrobial properties.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the bromine atoms can contribute to bioactivity and environmental stability.
• Organic Electronic Materials: Serves as a building block for conjugated molecules in the research of organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-rich pyrrole core.
• Ligand Synthesis for Catalysis: Employed in the preparation of specialized ligands for transition metal catalysis, facilitating challenging cross-coupling and other synthetic transformations.
• Polymer Functionalization: Acts as a monomer or functionalization agent to introduce bromine handles into polymers for further modification or to impart flame-retardant characteristics.
• Academic & R&D: A valuable tool for synthetic organic chemists in universities and corporate R&D labs exploring new heterocyclic chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	(3,4,5-Tribromo-1H-Pyrrole-2-Yl)(2-Hydroxy-5-Bromophenyl) Ketone
CAS No.	88217-19-0
Molecular Formula	C11H5Br4NO2
Molecular Weight	528.79 g/mol
Synonyms	2-Hydroxy-5-bromo-(3,4,5-tribromo-1H-pyrrol-2-yl)phenylmethanone; 1-(2-Hydroxy-5-bromophenyl)-3,4,5-tribromo-1H-pyrrol-2-yl methanone; (2-Hydroxy-5-bromophenyl)(3,4,5-tribromo-1H-pyrrol-2-yl)methanone; 5-Bromo-2-[(3,4,5-tribromo-1H-pyrrol-2-yl)carbonyl]phenol; Tribromopyrrole Ketone Derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of (3,4,5-Tribromo-1H-Pyrrole-2-Yl)(2-Hydroxy-5-Bromophenyl) Ketone is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.