Description

1-Propanone, 2-Fluoro-1-Phenyl-, (2R)- (9Ci) is a chiral, fluorinated aromatic ketone, serving as a valuable synthetic building block in advanced organic chemistry. Its core value lies in the precise stereochemistry and fluorine substitution, which are critical for modulating the biological activity and physicochemical properties of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of fluorinated active pharmaceutical ingredients (APIs), particularly in CNS and metabolic disease therapeutics.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides and herbicides, where the fluorine atom enhances lipophilicity and metabolic stability.
• Asymmetric Catalysis Research: A valuable probe or substrate in academic and industrial research focused on developing new fluorination and asymmetric synthesis methodologies.
• Ligand and Material Science Precursor: Serves as a starting material for synthesizing chiral ligands for catalysis or fluorinated monomers for specialty polymers.

Basic Information

Product Name	1-Propanone, 2-Fluoro-1-Phenyl-, (2R)- (9Ci)
CAS No.	88208-12-2
Molecular Formula	C9H9FO
Molecular Weight	152.16 g/mol
Synonyms	(R)-2-Fluoro-1-phenylethanone; (R)-α-Fluoroacetophenone; (2R)-2-Fluoro-1-phenylethan-1-one; (R)-1-Phenylethanone, 2-fluoro-; (R)-2-Fluoroacetophenone; (R)-(-)-2-Fluoroacetophenone; 2-Fluoroacetophenone, (R)-; 88208-12-2
EINECS	Contact for details

Quality Control

Our production of 1-Propanone, 2-Fluoro-1-Phenyl-, (2R)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.