Description

Cyclohexanone, 5-Ethyl-2-Fluoro-5-Hydroxy- is a functionalized cyclohexanone derivative, a key fluorinated intermediate in advanced organic synthesis. This compound matters for its unique structural features, combining a ketone group with fluorine and hydroxyl substituents, enabling precise molecular modifications. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs) and complex specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and durability.
• Advanced Polymer Modification: Employed to introduce fluorine and hydroxyl functional groups into polymer chains, altering surface properties and chemical resistance.
• Organic Synthesis Reagent: Acts as a versatile synthon in academic and industrial laboratories for constructing complex, stereodefined cyclic structures.

Basic Information

Product Name	Cyclohexanone, 5-Ethyl-2-Fluoro-5-Hydroxy-
CAS No.	88100-66-7
Molecular Formula	C8H13FO2
Molecular Weight	160.19 g/mol
Synonyms	5-Ethyl-2-fluoro-5-hydroxycyclohexan-1-one; 2-Fluoro-5-ethyl-5-hydroxycyclohexanone; 5-Hydroxy-5-ethyl-2-fluorocyclohexanone; Fluorinated Cyclohexanone Derivative; 88100-66-7; 5-Ethyl-5-hydroxy-2-fluorocyclohexanone; 2-Fluoro-5-hydroxy-5-ethylcyclohexanone
EINECS	Contact for details

Quality Control

Our Cyclohexanone, 5-Ethyl-2-Fluoro-5-Hydroxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and relevant pharmaceutical intermediate guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.