Description

(S)-1-Phosphono-3-Methyl-Butylamine CAS NO 88081-76-9 is a high-purity, chiral aminophosphonic acid derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and valuable building block for creating complex molecules with specific stereochemistry, which is critical for developing bioactive compounds. Pharmaceutical researchers and fine chemical manufacturers need it for applications in medicinal chemistry, particularly in the synthesis of enzyme inhibitors, prodrugs, and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel drug candidates, especially enzyme inhibitors.
• Medicinal Chemistry: Used in the design and synthesis of phosphonate-based prodrugs and bioactive molecules targeting various disease pathways.
• Agrochemical Research: Serves as a building block for developing new chiral herbicides, pesticides, and plant growth regulators with enhanced activity.
• Bioconjugation & Probe Development: Utilized in creating labeled compounds and molecular probes for biochemical and diagnostic research due to its phosphonate moiety.
• Ligand Synthesis for Catalysis: Acts as a precursor for chiral phosphine or phosphonate ligands used in asymmetric catalysis.
• Peptidomimetics: Incorporated into peptide analogs to enhance stability and modulate biological activity.

Basic Information

Product Name	(S)-1-Phosphono-3-Methyl-Butylamine
CAS No.	88081-76-9
Molecular Formula	C5H14NO3P
Molecular Weight	167.14 g/mol
Synonyms	(S)-3-Amino-4-methylpentylphosphonic acid; (S)-1-Amino-3-methylbutylphosphonic acid; (S)-AMPB; (S)-1-Phosphono-3-methylbutylamine; (S)-1-Amino-3-methylbutyl-1-phosphonic acid; L-1-Amino-3-methylbutylphosphonic acid; (3S)-3-Amino-4-methylpentylphosphonic acid
EINECS	Contact for details

Quality Control

Our (S)-1-Phosphono-3-Methyl-Butylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.