Description

Benzoic Acid, 3-(Bromomethyl)-4-Nitro-, Methyl Ester is a high-purity, synthetically valuable aromatic ester derivative, serving as a critical multifunctional building block in advanced organic synthesis. Its core value lies in the strategic combination of reactive bromomethyl and nitro substituents on the benzoate core, enabling precise molecular construction for complex target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is utilized in nucleophilic substitution reactions, cyclizations, and as a precursor to more elaborate heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in the synthesis of molecules with benzodiazepine or other fused heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators, leveraging its reactive sites for structural diversification.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of specialized ligands used in catalysis and molecular recognition studies.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where tailored aromatic esters modify material properties.
• Chemical Biology Probes: Useful for synthesizing activity-based probes or tagged molecules for studying biological pathways and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A versatile intermediate for custom chemical synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	Benzoic Acid, 3-(Bromomethyl)-4-Nitro-, Methyl Ester
CAS No.	88071-90-3
Molecular Formula	C9H8BrNO4
Molecular Weight	274.07 g/mol
Synonyms	Methyl 3-(Bromomethyl)-4-nitrobenzoate; 4-Nitro-3-(bromomethyl)benzoic Acid Methyl Ester; 3-Bromomethyl-4-nitrobenzoic Acid Methyl Ester; Benzoic acid, 3-(bromomethyl)-4-nitro-, methyl ester; Methyl 4-nitro-3-(bromomethyl)benzoate
EINECS	Contact for details

Quality Control

Every batch of Benzoic Acid, 3-(Bromomethyl)-4-Nitro-, Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical synthetic applications. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), identity (by IR and NMR), and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.