Description

n-[(3,3-Dimethylbutyl)dimethylsilyl]dimethylamine is a specialized organosilicon amine compound, serving as a versatile silylating agent and a key intermediate in advanced organic synthesis. Its primary value lies in its ability to introduce the bulky, lipophilic (3,3-dimethylbutyl)dimethylsilyl protecting group, which is crucial for modifying the properties of target molecules in pharmaceutical and material science research. This reagent is particularly sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty polymers, and advanced silicone materials.

Application

• Pharmaceutical Intermediate: Used as a key building block and protecting group reagent in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Silylation Agent: Employed to protect reactive functional groups (e.g., alcohols, amines) during complex organic synthesis, offering steric bulk for selective reactions.
• Material Science Research: Acts as a precursor or modifier in the development of novel silicone-based polymers, coatings, and hybrid organic-inorganic materials.
• Agrochemical Synthesis: Utilized in the research and development of advanced crop protection agents and specialty agrochemicals.
• Surface Modification: Applied to modify the surface properties of silica, glass, or other oxides to alter hydrophobicity, adhesion, or compatibility.
• Catalyst Ligand Synthesis: Serves as a starting material for creating novel ligand systems used in homogeneous catalysis.

Basic Information

Product Name	n-[(3,3-Dimethylbutyl)dimethylsilyl]dimethylamine
CAS No.	87810-61-5
Molecular Formula	C10H25NSi
Molecular Weight	187.40 g/mol
Synonyms	Dimethyl[(3,3-dimethylbutyl)dimethylsilyl]amine; (3,3-Dimethylbutyl)dimethyl(dimethylamino)silane; N,N-Dimethyl-1,1-dimethyl-1-(3,3-dimethylbutyl)silanamine; Dimethyl(3,3-dimethylbutyl)dimethylaminosilane; TBDMS-Dimethylamine; (Dimethylamino)(3,3-dimethylbutyl)dimethylsilane
EINECS	Contact for details

Quality Control

Our production of n-[(3,3-Dimethylbutyl)dimethylsilyl]dimethylamine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including GC, NMR, and Karl Fischer titration. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.