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(11R)-11,20-Epoxy-1β,2α,11,12α-Tetrahydroxypicrasane-16-One CAS NO 87733-58-2


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CAS No.:87733-58-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(11R)-11,20-Epoxy-1β,2α,11,12α-Tetrahydroxypicrasane-16-One is a highly oxidized and functionalized picrasane-type quassinoid, a class of compounds known for their complex structures and significant bioactivity. This specific stereoisomer is of considerable interest for advanced research and development in pharmacology and natural product chemistry due to its unique epoxy and polyhydroxylated framework. It serves as a critical reference standard and a potential synthetic intermediate for researchers in pharmaceutical discovery, agrochemical development, and academic institutions studying terpenoid biosynthesis and bioactivity.

Application

  • Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for quality control, method validation, and analytical testing in drug development pipelines.
  • Bioactive Compound Research: Serves as a lead compound or probe in pharmacological studies targeting various biological pathways, leveraging the known activity of quassinoids.
  • Natural Product Synthesis: Acts as a key chiral intermediate or target molecule in the total synthesis and semi-synthesis of complex terpenoids and related natural products.
  • Academic & Institutional Research: Utilized in universities and research institutes for structural elucidation, spectroscopic studies, and investigating structure-activity relationships (SAR).
  • Agrochemical Research: Explored for potential bioactivity in the development of new plant protection agents or growth regulators, given the historical use of quassinoids.

Basic Information

Product Name (11R)-11,20-Epoxy-1β,2α,11,12α-Tetrahydroxypicrasane-16-One
CAS No. 87733-58-2
Molecular Formula C20H28O7
Molecular Weight 380.43 g/mol
Synonyms 11,20-Epoxy-1β,2α,11,12α-tetrahydroxypicrasan-16-one; (11R)-11,20-Epoxy-1β,2α,11,12α-tetrahydroxypicrasan-16-one; Picrasane-16-one, 11,20-epoxy-1β,2α,11,12α-tetrahydroxy-, (11R)-; Quassinoid derivative; Oxidized picrasane diterpenoid
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Quality Control

Our high-purity (11R)-11,20-Epoxy-1β,2α,11,12α-Tetrahydroxypicrasane-16-One is manufactured under strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C to maximize stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Loss on Drying ≤ 2.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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