Description

(11R)-11,20-Epoxy-1β,6α,11,12α-Tetrahydroxypicrasa-3,13(21)-Diene-2,16-Dione is a highly specialized, bioactive quassinoid compound derived from natural sources, valued for its complex molecular architecture and potent biological activity. This compound is critical for advanced research and development in life sciences, serving as a key reference standard and a promising scaffold for novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on oncology, parasitology, and metabolic disease studies.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and identification of quassinoids in herbal extracts and finished pharmaceutical products.
• Bioactive Compound Research: Serves as a lead compound in pharmacological studies investigating anti-cancer, anti-malarial, and anti-inflammatory activities.
• Natural Product Chemistry: Essential for the isolation, characterization, and structural elucidation of complex terpenoids and related natural products.
• Drug Discovery & Development: Acts as a molecular scaffold for the semi-synthesis of novel derivatives with optimized pharmacokinetic and pharmacodynamic properties.
• Academic & Institutional Research: Utilized in university and government labs for fundamental studies on cell signaling pathways, apoptosis, and enzyme inhibition.
• Analytical Method Development: Employed as a benchmark for developing and validating advanced analytical methods such as HPLC-MS and NMR for complex matrix analysis.

Basic Information

Item	Details
Product Name	(11R)-11,20-Epoxy-1β,6α,11,12α-Tetrahydroxypicrasa-3,13(21)-Diene-2,16-Dione
CAS No.	87733-57-1
Molecular Formula	C20H24O7
Molecular Weight	376.40 g/mol
Synonyms	11,20-Epoxy-1β,6α,11,12α-tetrahydroxypicrasa-3,13(21)-diene-2,16-dione; (11R)-Picrasane derivative; Quassinoid SK1; Ailanthone analog; 1β,6α,11,12α-Tetrahydroxy-11,20-epoxypicrasa-3,13(21)-diene-2,16-dione; NSC 106572; Nigakilactone F related compound
EINECS	Contact for details

Quality Control

Every batch of (11R)-11,20-Epoxy-1β,6α,11,12α-Tetrahydroxypicrasa-3,13(21)-Diene-2,16-Dione is produced and analyzed under strict quality management systems. We provide comprehensive analytical documentation, including HPLC chromatograms and NMR spectra, to verify identity and purity. A Certificate of Analysis (COA) detailing batch-specific results for purity, related substances, and residual solvents is available for each shipment, ensuring full traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.