Description

2-Propen-1-One, 3-(Dimethylamino)-1-(2-Nitrophenyl)- is a specialized organic compound belonging to the class of α,β-unsaturated ketones (enones) with a nitroaromatic substituent. This unique structure makes it a valuable advanced pharmaceutical intermediate (API intermediate) and a versatile building block in fine chemical synthesis. It is primarily sought after by research institutions, pharmaceutical manufacturers, and agrochemical developers for the creation of novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting neurological or anti-infective pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its reactive enone and nitro groups.
• Dye and Pigment Synthesis: Acts as an intermediate for creating specialized nitroaromatic dyes and colorants.
• Organic Synthesis Building Block: Employed in Michael addition reactions and other C-C bond forming processes due to its activated double bond.
• Material Science Research: Investigated as a monomer or cross-linking agent for specialty polymers with unique optical or electronic properties.
• Academic & Industrial R&D: Utilized in chemical libraries for high-throughput screening and discovery chemistry programs.

Basic Information

Product Name	2-Propen-1-One, 3-(Dimethylamino)-1-(2-Nitrophenyl)-
CAS No.	87488-61-7
Molecular Formula	C11H12N2O3
Molecular Weight	220.23 g/mol
Synonyms	3-(Dimethylamino)-1-(2-nitrophenyl)-2-propen-1-one; 2-Nitrochalcone derivative; (E)-3-(Dimethylamino)-1-(2-nitrophenyl)prop-2-en-1-one; 1-(2-Nitrophenyl)-3-(dimethylamino)-2-propen-1-one; DMANP; Enaminone nitro derivative; β-Dimethylamino-2'-nitrochalcone
EINECS	Contact for details

Quality Control

We supply this high-purity intermediate under a rigorous quality management system. Each batch is manufactured and tested to meet exacting standards suitable for research and commercial synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with every shipment. Our production adheres to cGMP principles where required, ensuring traceability and consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging are performed under low-light conditions to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.