Description

Ethanone, 2,2,2-Trifluoro-1-[4-(Hydroxymethyl)Phenyl]- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a hydroxymethylphenyl functional group, making it a valuable fluorinated building block. This compound is significant for its role in introducing the trifluoroacetyl moiety into target molecules, which can dramatically alter physical, chemical, and biological properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of drug candidates, particularly those requiring the metabolically stable trifluoromethyl group to enhance bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where fluorine incorporation improves efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic compounds for electronic displays and lighting applications.
• Advanced Polymer Chemistry: Employed as a monomer or cross-linking agent to create specialty polymers with unique thermal and chemical resistance profiles.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new fluorination methodologies and creating complex molecular architectures.
• Coordination Chemistry Ligand: The ketone and hydroxymethyl groups can act as binding sites for metal ions, useful in catalyst design and material science.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-[4-(Hydroxymethyl)Phenyl]- (9Ci)
CAS No.	87437-75-0
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	1-[4-(Hydroxymethyl)phenyl]-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-[4-(hydroxymethyl)phenyl]ethanone; 4-(Trifluoroacetyl)benzyl alcohol; p-(Trifluoroacetyl)benzyl alcohol; α,α,α-Trifluoro-4-(hydroxymethyl)acetophenone; 4-(Hydroxymethyl)phenyl trifluoromethyl ketone; Benzyl alcohol, 4-(trifluoroacetyl)-
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-[4-(Hydroxymethyl)Phenyl]- (9Ci) is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. For specific project requirements, including custom purity grades or analytical method validation, please contact our technical support team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.