Description

Ethyl 1-Phenylcyclopropanecarboxylate is a high-value organic ester building block featuring a cyclopropane ring fused with a phenyl group. This compound matters as a versatile synthetic intermediate, prized for its unique strained-ring structure which can impart specific reactivity and properties in advanced chemical synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the cyclopropane moiety can enhance biological activity.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and advanced organic materials with tailored properties.
• Organic Synthesis & Methodology Development: A valuable substrate in academic and industrial research for studying ring-opening reactions and cyclopropane chemistry.
• Flavor & Fragrance Industry: Potential intermediate for creating complex ester-based aroma chemicals, though specific applications require evaluation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthesis projects.

Basic Information

Product Name	Ethyl 1-Phenylcyclopropanecarboxylate
CAS No.	87328-17-4
Molecular Formula	C12H14O2
Molecular Weight	190.24 g/mol
Synonyms	1-Phenylcyclopropanecarboxylic Acid Ethyl Ester; Ethyl 1-Phenyl-1-cyclopropanecarboxylate; Ethyl Phenylcyclopropanecarboxylate; 1-Phenylcyclopropanecarboxylic Acid Ethyl Ester; Ethyl 1-Phenylcyclopropane-1-carboxylate; NSC 403820; Ethyl α-Phenylcyclopropanecarboxylate; Cyclopropanecarboxylic acid, 1-phenyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-Phenylcyclopropanecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results from tests including assay (by GC/HPLC), identification (IR/NMR), and impurity profile analysis. We adhere to cGMP principles where applicable to support our customers in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Purity (GC Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.