Description

4-Boc-Styrene is a protected styrene derivative where the hydroxyl group of 4-vinylphenol is shielded by a tert-butoxycarbonyl (Boc) protecting group. This compound is a crucial high-purity building block in organic synthesis, valued for its role in introducing a polymerizable vinyl group while maintaining orthogonally protected functionality. It is primarily utilized by pharmaceutical researchers and specialty polymer chemists for developing advanced materials, drug candidates, and functional monomers. CAS NO 87261-04-9.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and prodrugs.
• Polymer Chemistry: Serves as a functional monomer for creating specialty polymers with pendant protected-phenol groups, enabling precise post-polymerization modifications.
• Material Science Research: Used in the development of advanced materials, including stimuli-responsive polymers, coatings, and resins with tailored properties.
• Cross-coupling Reactions: The vinyl group can participate in various catalytic reactions, such as Heck coupling, to construct more complex molecular architectures.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and new reaction pathway exploration.

Basic Information

Product Name	4-Boc-Styrene
CAS No.	87261-04-9
Molecular Formula	C13H16O2
Molecular Weight	204.26 g/mol
Synonyms	4-(tert-Butoxycarbonyloxy)styrene; 4-Vinylphenyl tert-butyl carbonate; 4-(tert-Butyloxycarbonyloxy)styrene; 4-BocO-Styrene; tert-Butyl (4-vinylphenyl) carbonate; 4-(Bocoxy)styrene; 4-Styrenyl tert-butyl carbonate; p-Vinylphenyl tert-butyl carbonate
EINECS	Contact for details

Quality Control

Our 4-Boc-Styrene is manufactured under strict quality protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development as well as pre-clinical scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.