Description

3-Hydroxyphenylboronic Acid is a versatile organoboron compound featuring both a boronic acid group and a phenolic hydroxyl group on an aromatic ring. This bifunctional structure makes it a valuable key intermediate in modern synthetic chemistry, particularly for cross-coupling reactions and the construction of complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors who require high-purity building blocks for drug discovery, catalyst development, and polymer synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A fundamental building block for creating biaryl and heterobiaryl structures, which are core motifs in many active pharmaceutical ingredients (APIs) and organic electronic materials.
• Pharmaceutical Intermediate: Used in the synthesis of potential drug candidates, including kinase inhibitors, antiviral agents, and other biologically active molecules.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science & Polymer Chemistry: Employed in the creation of advanced polymers, covalent organic frameworks (COFs), and sensors due to its ability to form stable boronate esters.
• Chemical Biology & Proteomics: Utilized as a handle for bioconjugation and in the development of chemical probes that target proteins or carbohydrates.
• Ligand for Catalysis: Can be used to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Item	Details
Product Name	3-Hydroxyphenylboronic Acid
CAS No.	87199-18-6
Molecular Formula	C6H7BO3
Molecular Weight	137.93 g/mol
Synonyms	(3-Hydroxyphenyl)boronic acid; 3-Hydroxybenzeneboronic Acid; m-Hydroxyphenylboronic Acid; 3-Boronophenol; 3-Hydroxybenzeneboronic acid; Boronic acid, B-(3-hydroxyphenyl)-; 3-Hydroxy Phenyl Boronic Acid; m-Hydroxybenzeneboronic Acid
EINECS	Contact for details

Quality Control

Our 3-Hydroxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Water Content (KF)	≤1.0%
Melting Point	~200-210°C (dec.)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.