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3-(Hydroxymethyl)Phenylboronic Acid CAS NO 87199-15-3


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CAS No.:87199-15-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(Hydroxymethyl)Phenylboronic Acid is a versatile bifunctional organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in the combination of a reactive boronic acid group and a hydroxymethyl substituent on the same aromatic ring, enabling sequential and selective chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for constructing complex molecules via Suzuki-Miyaura cross-coupling reactions and other catalytic processes.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially in oncology and CNS therapeutic areas.
  • Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific aromatic architectures.
  • Material Science & OLEDs: Serves as a monomer or precursor for creating organic electronic materials, including polymers for organic light-emitting diodes (OLEDs) and conductive films.
  • Suzuki-Miyaura Cross-Coupling: A fundamental reagent for forming carbon-carbon bonds between aromatic rings, a cornerstone reaction in medicinal and process chemistry.
  • Chemical Biology & Proteomics: Utilized in the development of molecular probes, enzyme inhibitors, and bioconjugation agents due to its selective reactivity.
  • Ligand Synthesis for Catalysis: Precursor for synthesizing sophisticated ligands used in homogeneous catalysis and asymmetric synthesis.

Basic Information

Product Name 3-(Hydroxymethyl)Phenylboronic Acid
CAS No. 87199-15-3
Molecular Formula C7H9BO3
Molecular Weight 151.96 g/mol
Synonyms (3-(Hydroxymethyl)phenyl)boronic acid; m-(Hydroxymethyl)benzeneboronic acid; 3-Carbinolphenylboronic acid; (3-Hydroxymethylphenyl)boronic acid; B-(3-Hydroxymethylphenyl)boronic acid; 3-Hydroxymethylbenzeneboronic acid; 87199-15-3; AI3-52362
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Quality Control

Our 3-(Hydroxymethyl)Phenylboronic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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