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2-Hydroxymethylphenylboronic Acid CAS NO 87199-14-2
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CAS No.:87199-14-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-Hydroxymethylphenylboronic Acid is a versatile organoboron compound featuring both a boronic acid and a hydroxymethyl functional group on the aromatic ring. This bifunctional structure makes it a valuable building block in modern synthetic chemistry, particularly for the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex molecule synthesis. Our supply ensures consistent quality and reliable availability for your critical R&D and production needs.
Application
- Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, especially in oncology and CNS therapeutic areas.
- Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific aryl-boronic acid precursors.
- Suzuki-Miyaura Cross-Coupling: A crucial reagent for palladium-catalyzed cross-coupling reactions to create biaryl structures, a common motif in many functional molecules.
- Ligand and Catalyst Development: Serves as a precursor for creating novel ligands and organometallic catalysts used in asymmetric synthesis.
- Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and organic photovoltaics.
- Chemical Biology Probes: Utilized in the development of molecular probes and sensors that leverage boronic acid-diol interactions.
Basic Information
| Product Name | 2-Hydroxymethylphenylboronic Acid |
| CAS No. | 87199-14-2 |
| Molecular Formula | C7H9BO3 |
| Molecular Weight | 151.96 g/mol |
| Synonyms | (2-(Hydroxymethyl)phenyl)boronic acid; 2-(Hydroxymethyl)benzeneboronic acid; o-(Hydroxymethyl)phenylboronic acid; 2-Hydroxymethylbenzeneboronic acid; B-(2-Hydroxymethylphenyl)boronic acid; 2-Boronobenzyl alcohol; (2-Hydroxymethyl)phenylboronic acid |
| EINECS | Contact for details |
Quality Control
Our 2-Hydroxymethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and compliance with your specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 1.0% |
| Melting Point | Contact for details |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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