Description

2-Chloro-4-Nitrophenacyl Bromide is a versatile and reactive organic intermediate of significant importance in synthetic chemistry. Its value lies in its bifunctional halogenated and nitro-substituted aromatic structure, making it a key building block for constructing more complex molecules. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents where the nitro and chloro groups impart specific biological activity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and as a starting material for heterocyclic compound synthesis in academic and industrial R&D.
• Material Science Research: Acts as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Derivatization Agent: Utilized for analytical purposes or to modify the properties of other compounds via its reactive phenacyl bromide group.

Basic Information

Product Name	2-Chloro-4-Nitrophenacyl Bromide
CAS No.	87154-68-5
Molecular Formula	C8H5BrClNO3
Molecular Weight	278.49 g/mol
Synonyms	2-Bromo-1-(2-chloro-4-nitrophenyl)ethan-1-one; 2-Bromo-2'-chloro-4'-nitroacetophenone; α-Bromo-2-chloro-4-nitroacetophenone; Phenacyl bromide, 2-chloro-4-nitro-; 1-(2-Chloro-4-nitrophenyl)-2-bromoethanone; (2-Chloro-4-nitrophenyl)bromomethyl ketone; Bromo(2-chloro-4-nitrophenyl)methanone
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Nitrophenacyl Bromide is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.