Description

(5-Phenyl-4H-1,2,4-Triazol-3-Yl)Acetonitrile is a high-value, nitrogen-rich heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile precursor in the development of novel pharmacologically active molecules and functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of triazole-containing drug candidates, including potential kinase inhibitors, antifungal agents, and CNS-active compounds.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators that leverage the triazole moiety's bioactivity.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of advanced polymers and organic electronic materials due to its rigid, conjugated structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Scale-Up: A critical starting material for contract research organizations (CROs) and CDMOs offering custom synthesis services.

Basic Information

Product Name	(5-Phenyl-4H-1,2,4-Triazol-3-Yl)Acetonitrile
CAS No.	86999-29-3
Molecular Formula	C10H8N4
Molecular Weight	184.20 g/mol
Synonyms	2-(5-Phenyl-4H-1,2,4-triazol-3-yl)acetonitrile; 3-Cyanomethyl-5-phenyl-1,2,4-triazole; 5-Phenyl-1H-1,2,4-triazole-3-acetonitrile; (5-Phenyl-1H-1,2,4-triazol-3-yl)acetonitrile; 86999-29-3; Acetonitrile, (5-phenyl-4H-1,2,4-triazol-3-yl)-
EINECS	Contact for details

Quality Control

Our (5-Phenyl-4H-1,2,4-Triazol-3-Yl)Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.