Description

6-o-Methylerythromycin B is a semi-synthetic derivative of the macrolide antibiotic erythromycin. This compound is valued for its role as a key intermediate in the research and development of novel antibacterial agents, particularly for exploring structure-activity relationships. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on advanced antibiotic synthesis and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of next-generation macrolide antibiotics.
• Antibacterial Research: Used in microbiological and pharmacological studies to investigate new mechanisms of action against resistant bacterial strains.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization studies for the production of specialized antibiotic compounds.
• Academic Research: Utilized in university and institutional labs for chemical and biological research pertaining to antibiotic modification.

Basic Information

Product Name	6-o-Methylerythromycin B
CAS No.	86976-45-6
Molecular Formula	C38H67NO13
Molecular Weight	745.94 g/mol
Synonyms	6-O-Methylerythromycin B; Erythromycin B, 6-O-methyl-; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]oxacyclotetradecane-2,10-dione; 6-O-Me-Ery B
EINECS	Contact for details

Quality Control

Our 6-o-Methylerythromycin B is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.