Description

Acth (1-37) CAS NO 86836-91-1 is a synthetic peptide fragment of the adrenocorticotropic hormone (ACTH), representing the biologically active N-terminal sequence. This high-purity peptide is critical for research and development in endocrinology and metabolic studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on hormone-related therapeutics and diagnostic assay development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of adrenal cortex function, steroidogenesis, and the hypothalamic-pituitary-adrenal (HPA) axis.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of diagnostic kits and potential therapeutic agents for adrenal disorders.
• Biochemical Assays: Employed in in vitro and cell-based assays to investigate ACTH receptor (MC2R) binding, signaling pathways, and cellular responses.
• Standards and Calibration: Functions as a high-purity calibration standard in analytical techniques such as HPLC and mass spectrometry for quantitative analysis.
• Neuroscience Research: Investigated for its potential neuromodulatory and neuroprotective effects in central nervous system research.

Basic Information

Product Name	Acth (1-37)
CAS No.	86836-91-1
Molecular Formula	C₉₀H₁₃₀N₂₄O₂₈S
Molecular Weight	2047.2 g/mol
Synonyms	Adrenocorticotropic Hormone (1-37); ACTH (1-37); Corticotropin (1-37); Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asp-Ala-Gly-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe; H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asp-Ala-Gly-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH
EINECS	Contact for details

Quality Control

Our Acth (1-37) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets rigorous standards for research and development use. Certificates of Analysis (COA) detailing purity, peptide content, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.