Description

Adrenocorticotropin Zinc CAS NO 53468-06-7 is a zinc-complexed form of the peptide hormone adrenocorticotropin (ACTH), designed to provide a sustained-release profile. This formulation is critical for ensuring consistent biological activity and enhanced stability in therapeutic applications. It is primarily utilized in pharmaceutical research and development, as well as in the production of diagnostic reagents for endocrine function testing.

Application

• Pharmaceutical Intermediate: Serves as a key active pharmaceutical ingredient (API) or intermediate in the synthesis of long-acting hormonal therapies.
• Endocrine Research: Used in laboratory studies to investigate adrenal cortex function, steroidogenesis, and the hypothalamic-pituitary-adrenal (HPA) axis.
• Diagnostic Reagent Manufacturing: Employed in the production of in-vitro diagnostic (IVD) kits for assessing adrenal gland disorders, such as Addison's disease or Cushing's syndrome.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Veterinary Medicine: Applied in veterinary pharmaceuticals for diagnostic and therapeutic purposes in animals.

Basic Information

Product Name	Adrenocorticotropin Zinc
CAS No.	53468-06-7
Molecular Formula	C207H308N56O58SZn
Molecular Weight	Approx. 4560 g/mol (as zinc complex)
Synonyms	ACTH Zinc; Adrenocorticotropic Hormone Zinc Complex; Corticotropin Zinc; Zinc-Adrenocorticotropin; 1-39-Corticotropin Zinc; Cosyntropin Zinc; Tetracosactide Zinc; ACTH (1-39) Zinc Salt
EINECS	Contact for details

Quality Control

Our Adrenocorticotropin Zinc is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including purity assay, peptide content, zinc content determination, and related substance profiling to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) are provided and can be tailored to meet specific pharmacopeial requirements (e.g., USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (Peptide Content)	≥ 95.0% (on anhydrous basis)
Zinc Content	2.0% - 4.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Biological Potency	Assigned per batch (IU/mg)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.