Description

Cyclobutanecarboxamide, 3,3-Difluoro- (9Ci) CAS NO 86770-82-3 is a high-purity, fluorinated cyclobutane derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a difluorinated cyclobutane ring, makes it a valuable intermediate for developing novel compounds with enhanced stability and specific biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing the metabolically stable difluorocyclobutyl moiety.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorinated cyclobutane structure can improve efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers and advanced materials requiring specific fluorine-containing functional groups.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the synthesis of novel ligands and catalysts used in asymmetric synthesis.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the properties and reactivity of fluorinated alicyclic systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	Cyclobutanecarboxamide, 3,3-Difluoro- (9Ci)
CAS No.	86770-82-3
Molecular Formula	C5H7F2NO
Molecular Weight	135.11 g/mol
Synonyms	3,3-Difluorocyclobutanecarboxamide; 3,3-Difluorocyclobutanecarboxylic acid amide; 3,3-Difluorocyclobutane-1-carboxamide; NSC 405124; 1-Carbamoyl-3,3-difluorocyclobutane; 3,3-Difluoro-1-cyclobutanecarboxamide; 3,3-Difluorocyclobutylcarboxamide
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanecarboxamide, 3,3-Difluoro- (9Ci) is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent exposure to atmospheric moisture, which can affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.