Description

(1S,3Z,8R)-3-(1-Bromopropylidene)-6β-Chloro-5β-[(Z)-2-Penten-4-Ynyl]-4,9-Dioxabicyclo[6.1.0]Nonane CAS NO 86747-06-0 is a high-purity, structurally complex organic intermediate featuring a bicyclic framework with halogen and alkyne functional groups. This compound is valued for its precise stereochemistry and reactive sites, making it a critical building block for advanced synthetic chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the multi-step synthesis of potential drug candidates, particularly in oncology and antiviral research.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its unique structure can contribute to novel modes of action.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialized polymers with tailored thermal or mechanical properties.
• Academic & R&D: Employed in methodological studies and total synthesis projects to explore new chemical transformations and construct complex molecular architectures.
• Ligand & Catalyst Development: The alkyne and halogen functionalities make it a useful scaffold for creating novel ligands for asymmetric catalysis.

Basic Information

Product Name	(1S,3Z,8R)-3-(1-Bromopropylidene)-6β-Chloro-5β-[(Z)-2-Penten-4-Ynyl]-4,9-Dioxabicyclo[6.1.0]Nonane
CAS No.	86747-06-0
Molecular Formula	C15H16BrClO2
Molecular Weight	343.64 g/mol
Synonyms	6β-Chloro-5β-[(1Z)-1-buten-3-yn-1-yl]-3-[(1Z)-1-bromopropylidene]-4,9-dioxabicyclo[6.1.0]nonane; (1S,3Z,8R)-3-(1-Bromopropylidene)-6β-chloro-5β-[(Z)-2-penten-4-ynyl]-4,9-dioxabicyclo[6.1.0]nonane; 4,9-Dioxabicyclo[6.1.0]nonane derivative; Bicyclic bromo-chloro enyne ether; CAS 86747-06-0.
EINECS	Contact for details

Quality Control

Every batch of (1S,3Z,8R)-3-(1-Bromopropylidene)-6β-Chloro-5β-[(Z)-2-Penten-4-Ynyl]-4,9-Dioxabicyclo[6.1.0]Nonane is produced and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and isomeric purity and batch-to-batch consistency. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.