Description

2-Butanone, 3-Chloro-4-Fluoro- (9Ci) is a halogenated derivative of butanone, serving as a versatile and reactive organic intermediate. This compound is valued for its ability to introduce both chloro and fluoro substituents into target molecules, enabling precise structural modifications in advanced synthesis. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring specific halogenated motifs for bioactivity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the chloro-fluoro pattern enhances stability and efficacy.
• Organic Synthesis Reagent: Employed in research laboratories for constructing complex organic frameworks, including heterocycles and fluorinated compounds.
• Material Science Precursor: Acts as a starting material for synthesizing specialized monomers or ligands used in polymer and catalyst development.
• Fluorine Chemistry: Serves as a valuable source of a fluorine-containing moiety in medicinal chemistry and materials science research.

Basic Information

Product Name	2-Butanone, 3-Chloro-4-Fluoro- (9Ci)
CAS No.	86727-59-5
Molecular Formula	C₄H₆ClFO
Molecular Weight	124.54 g/mol
Synonyms	3-Chloro-4-fluorobutan-2-one; 1-Chloro-1-fluoro-2-butanone; 3-Chloro-4-fluoro-2-butanone; 4-Fluoro-3-chloro-2-butanone; 2-Butanone, 3-chloro-4-fluoro-; Butan-2-one, 3-chloro-4-fluoro-; 3-Chloro-4-fluorobutanone; 1-Fluoro-1-chloro-2-butanone
EINECS	Contact for details

Quality Control

Our 2-Butanone, 3-Chloro-4-Fluoro- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and reducing agents. Due to its nature as a strong acid/organic solvent and highly volatile compound, appropriate secondary containment and vapor control measures are recommended. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.