Description

Diisopropoxymethylborane is a versatile organoboron reagent, specifically a methylboronic ester, widely used in organic synthesis and advanced material science. Its primary value lies in its role as a crucial methyl transfer agent and a stable precursor for generating reactive borane species under controlled conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, where precise carbon-boron bond formation is required for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a methylboron source for introducing methyl groups into aromatic and heteroaromatic systems, a key step in pharmaceutical intermediate synthesis.
• Asymmetric Synthesis: Serves as a reagent in the preparation of chiral organoboron compounds for the production of enantiomerically pure active pharmaceutical ingredients (APIs).
• Polymer Modification: Utilized as a functionalization agent to introduce boron-containing groups into polymer backbones, modifying thermal and electronic properties for advanced materials.
• Hydroboration Reactions: Functions as a hydroborating agent for alkenes and alkynes, providing access to alkylboranes for further synthetic transformations.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of boron-based electron-transport materials and emitters for display and lighting technologies.
• Agrochemical Synthesis: Used in creating boron-containing bioactive molecules with herbicidal or insecticidal properties.

Basic Information

Product Name	Diisopropoxymethylborane
CAS No.	86595-27-9
Molecular Formula	C7H17BO2
Molecular Weight	144.02 g/mol
Synonyms	Methyldiisopropoxyborane; Methylboronic Acid Diisopropyl Ester; Diisopropyl Methylboronate; (Isopropoxy)methylborinic Acid Isopropyl Ester; B-Methylboronic Acid Diisopropyl Ester; Diisopropoxymethylboron; Methyl Diisopropyloxyborane
EINECS	Contact for details

Quality Control

Our Diisopropoxymethylborane is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot undergoes comprehensive analytical testing, including NMR, GC, and titration methods, to verify identity, assay, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our rigorous internal specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Assay (GC)	≥ 95.0%
Purity (by 11B NMR)	≥ 97.0%
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.