Description

1-(4-Chloro-2-Trifluoromethyl-Phenyl)-Ethanone is a high-purity, versatile organic intermediate characterized by its distinct aromatic ketone structure with chloro and trifluoromethyl substituents. This compound is critical for its role in synthesizing advanced molecules, offering a unique combination of electronic and steric properties that are difficult to achieve with simpler building blocks. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in the development of molecules targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for liquid crystals, organic semiconductors, and other advanced functional materials due to its rigid, fluorinated aromatic structure.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, catalysis studies, and exploring new reaction pathways in organic chemistry.
• Fine Chemical Production: An essential intermediate for manufacturing dyes, pigments, and other specialty chemicals requiring specific halogenated and fluorinated motifs.

Basic Information

Product Name	1-(4-Chloro-2-Trifluoromethyl-Phenyl)-Ethanone
CAS No.	86520-34-5
Molecular Formula	C9H6ClF3O
Molecular Weight	222.59 g/mol
Synonyms	4'-Chloro-2'-(trifluoromethyl)acetophenone; 1-(4-Chloro-2-(trifluoromethyl)phenyl)ethan-1-one; 2-Trifluoromethyl-4-chloroacetophenone; 4-Chloro-α,α,α-trifluoro-2-acetophenone; p-Chloro-o-trifluoromethylacetophenone; 86520-34-5; Ethanone, 1-[4-chloro-2-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-(4-Chloro-2-Trifluoromethyl-Phenyl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), impurity profiles, and physical characteristics. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.