Description

2,4''-Difluor-2-(1H-1,2,4-Triazool-1-Yl)Acetofenonhydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific fluorinated triazole structure. This compound is of critical importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antifungal and other therapeutic areas. It is primarily needed by research institutions, custom synthesis organizations, and pharmaceutical manufacturers engaged in the development and scale-up of new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of complex antifungal agents and other specialized active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new therapeutic compounds.
• Custom Synthesis: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific molecules on a commercial scale.
• Chemical Reference Standard: Acts as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical laboratories.

Basic Information

Product Name	2,4''-Difluor-2-(1H-1,2,4-Triazool-1-Yl)Acetofenonhydrochloride
CAS No.	86386-75-6
Molecular Formula	C10H7ClF2N3O
Molecular Weight	258.63 g/mol
Synonyms	2,4'-Difluoro-2-(1H-1,2,4-triazol-1-yl)acetophenone hydrochloride; 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone hydrochloride; 86386-75-6; Difluorotriazolylacetophenone HCl; α-(1H-1,2,4-Triazol-1-yl)-2,4-difluoroacetophenone hydrochloride
EINECS	Contact for details

Quality Control

Our 2,4''-Difluor-2-(1H-1,2,4-Triazool-1-Yl)Acetofenonhydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.