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2-[[(3A,5B,7B,12A)-3,7,12-Trihydroxy-24-Oxocholan-24-Yl]Amino]-Ethanesulfonic Acid CAS NO 86386-60-9


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CAS No.:86386-60-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-[[(3A,5B,7B,12A)-3,7,12-Trihydroxy-24-Oxocholan-24-Yl]Amino]-Ethanesulfonic Acid is a high-purity bile acid derivative, specifically a taurine conjugate, valued for its role as a critical biochemical intermediate and reference standard. This compound matters for its utility in advanced pharmaceutical research, particularly in the study of bile acid metabolism, liver function, and the development of diagnostic assays. It is primarily needed by research institutions, pharmaceutical developers, and manufacturers of in-vitro diagnostic kits who require precise and reliable biochemical tools.

Application

  • Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel therapeutic agents targeting liver and metabolic disorders.
  • Biochemical Reference Standard: Used for the calibration of analytical equipment (HPLC, LC-MS) and as a purity benchmark in quality control laboratories.
  • Diagnostic Reagent Manufacturing: An essential component in the formulation of enzymatic and immunoassay kits for clinical diagnostics, particularly for liver function tests.
  • Metabolic Pathway Studies: Employed in academic and industrial research to investigate bile acid synthesis, transport, and signaling pathways.
  • Cell Culture & Biotechnology: May be used in specialized cell culture media or as a biochemical modulator in bioprocessing applications.

Basic Information

Product Name 2-[[(3A,5B,7B,12A)-3,7,12-Trihydroxy-24-Oxocholan-24-Yl]Amino]-Ethanesulfonic Acid
CAS No. 86386-60-9
Molecular Formula C₂₆H₄₅NO₇S
Molecular Weight 515.71 g/mol
Synonyms Taurocholic Acid Impurity; Taurocholic Acid Related Compound; 3α,7α,12α-Trihydroxy-5β-cholan-24-oic Acid N-(2-Sulfoethyl)amide; Tauro-3α,7α,12α-trihydroxy-5β-cholan-24-oate; Taurocholate Derivative; 24-Tauroamidocholic Acid; N-(2-Sulfoethyl)-3α,7α,12α-trihydroxy-5β-cholan-24-amide
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Quality Control

Our 2-[[(3A,5B,7B,12A)-3,7,12-Trihydroxy-24-Oxocholan-24-Yl]Amino]-Ethanesulfonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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