Description

2-Bromo-1-(4-Nitrophenyl)Ethanone is a versatile brominated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its core value lies in its reactive bromomethyl ketone moiety adjacent to an electron-withdrawing nitro group, making it a key building block for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as heterocyclic synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of various heterocyclic compounds and potential active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Chemical Research: Acts as a versatile electrophile in organic synthesis for C-C and C-N bond-forming reactions, including alkylations and nucleophilic substitutions.
• Material Science: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex aromatic dyes and functional pigments.

Basic Information

Product Name	2-Bromo-1-(4-Nitrophenyl)Ethanone
CAS No.	86379-85-3
Molecular Formula	C8H6BrNO3
Molecular Weight	244.04 g/mol
Synonyms	2-Bromo-4'-Nitroacetophenone; 4'-Nitro-2-bromoacetophenone; 2-Bromo-1-(4-nitrophenyl)ethan-1-one; p-Nitro-α-bromoacetophenone; α-Bromo-4-nitroacetophenone; 1-(4-Nitrophenyl)-2-bromoethanone; 2-Bromo-4-nitroacetophenone; NSC 404083
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(4-Nitrophenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, the container should be amber-colored or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.