Description

Hexylboronic Acid Pinacol Ester is a high-purity organoboron reagent, specifically a protected boronic acid derivative. This compound is valued for its enhanced stability and handling properties compared to its free boronic acid counterpart, making it a crucial building block in modern synthetic chemistry. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for cross-coupling reactions and other advanced synthetic transformations.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules, including pharmaceutical intermediates and active ingredients.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of new drug candidates, particularly for introducing hexyl or modified alkyl chains.
• Agrochemical Production: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Materials Science Research: Employed in the development of organic electronic materials, polymers, and liquid crystals.
• Chemical Biology & Medicinal Chemistry: Useful for bioconjugation and as a probe in the study of biological processes.
• Process Chemistry & Scale-up: Its pinacol ester form offers improved stability for handling in large-scale manufacturing processes.

Basic Information

Product Name	Hexylboronic Acid Pinacol Ester
CAS No.	86308-26-1
Molecular Formula	C₁₂H₂₅BO₂
Molecular Weight	212.14 g/mol
Synonyms	Hexylboronic Acid Pinacol Ester; Pinacol Hexylboronate; 4,4,5,5-Tetramethyl-2-hexyl-1,3,2-dioxaborolane; 2-Hexyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; HexylBpin; n-Hexylboronic Acid Pinacol Ester; B-Hexyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; HexylBPin
EINECS	Contact for details

Quality Control

Our Hexylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (GC/NMR). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.