Description

2-Butenoic Acid, 4,4,4-Trifluoro-3-Hydroxy- is a fluorinated hydroxybutenoic acid derivative, a specialized building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a trifluoromethyl group and a hydroxyl moiety on an unsaturated acid backbone, makes it a valuable precursor for creating molecules with enhanced biological activity and physicochemical properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated drug candidates, particularly in areas like enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the introduction of fluorine atoms can improve metabolic stability and bioavailability.
• Advanced Material Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers and coatings with tailored surface properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new fluorination methodologies and constructing complex molecular architectures.
• Ligand and Catalyst Development: Useful for synthesizing chiral ligands or metal-organic complexes used in asymmetric catalysis.

Basic Information

Product Name	2-Butenoic Acid, 4,4,4-Trifluoro-3-Hydroxy-
CAS No.	86302-40-1
Molecular Formula	C4H3F3O3
Molecular Weight	156.06 g/mol
Synonyms	4,4,4-Trifluoro-3-hydroxy-2-butenoic acid; 3-Hydroxy-4,4,4-trifluorobut-2-enoic acid; 4,4,4-Trifluoro-3-hydroxycrotonic acid; TFMHA; (Z)-4,4,4-Trifluoro-3-hydroxybut-2-enoic Acid; (E)-4,4,4-Trifluoro-3-hydroxybut-2-enoic Acid; 3-Hydroxy-4,4,4-trifluorocrotonic acid
EINECS	Contact for details

Quality Control

Our 2-Butenoic Acid, 4,4,4-Trifluoro-3-Hydroxy- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.