Description

2-[2-[2-[2-(Benzyloxy)Ethoxy]Ethoxy]Ethoxy]Ethanol is a specialized polyethylene glycol (PEG) derivative featuring a benzyl-protected terminal hydroxyl group. This molecular structure is critical for its role as a versatile building block and linker in advanced organic synthesis and material science. It is primarily sought by R&D and production teams in the pharmaceutical, polymer, and specialty chemical industries for creating functionalized materials, prodrugs, and non-ionic surfactants with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key spacer or linker molecule in the synthesis of prodrugs, antibody-drug conjugates (ADCs), and PEGylated therapeutic agents to enhance solubility and bioavailability.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent for synthesizing specialized polyethers, hydrogels, and biocompatible polymers with controlled architecture.
• Surface Modification: Used to create hydrophilic coatings and functionalize surfaces (e.g., nanoparticles, silica, medical devices) to impart antifouling or specific binding properties.
• Non-ionic Surfactant/Solvent: Employed in formulations requiring a hydrophilic-lipophilic balance (HLB), such as in specialty detergents, emulsifiers, and solubilizing agents.
• Chemical Synthesis: Utilized as a protected polyether synthon in multi-step organic synthesis, where the benzyl group allows for selective deprotection strategies.
• Material Science Research: A valuable reagent for developing novel functional materials, including dendrimers, star polymers, and smart delivery systems.

Basic Information

Product Name	2-[2-[2-[2-(Benzyloxy)Ethoxy]Ethoxy]Ethoxy]Ethanol
CAS No.	86259-87-2
Molecular Formula	C15H24O6
Molecular Weight	300.35 g/mol
Synonyms	Benzyl tetraethylene glycol; Tetraethylene glycol monobenzyl ether; 2,5,8,11-Tetraoxatetradecan-14-ol, 13-(phenylmethoxy)-; PEG4 benzyl ether; Benzyl-PEG4-OH; 13-(Benzyloxy)-2,5,8,11-tetraoxatetradecan-14-ol; α-Benzyl-ω-hydroxy-tetraethylene glycol
EINECS	Contact for details

Quality Control

Every batch of 2-[2-[2-[2-(Benzyloxy)Ethoxy]Ethoxy]Ethoxy]Ethanol undergoes rigorous analytical testing to ensure high purity and consistency suitable for sensitive applications. Our quality assurance protocols are designed to meet the stringent requirements of research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.