Description

3-Fluoro-5-(Trifluoromethoxy)Benzyl Bromide, 97% is a high-purity, multi-functional benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of fluorine and bromine substituents, which enable precise molecular modifications to enhance the properties of target compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethoxy groups contribute to bioavailability and environmental stability.
• Liquid Crystal & OLED Material Development: Acts as a building block for creating fluorinated aromatic cores in electronic and display materials, improving charge transport and thermal properties.
• Cross-Coupling Reactions: The reactive benzyl bromide moiety facilitates Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions for constructing complex biaryl systems.
• Functional Polymer Modification: Employed to introduce fluorinated benzyl groups into polymer backbones, enhancing chemical resistance and surface characteristics.
• Chemical Biology & Proteomics: Useful for synthesizing affinity probes, enzyme inhibitors, and molecular tags that exploit the unique electronic properties of fluorine.

Basic Information

Product Name	3-Fluoro-5-(Trifluoromethoxy)Benzyl Bromide, 97%
CAS No.	86256-51-1
Molecular Formula	C9H5BrF4O
Molecular Weight	285.04 g/mol
Synonyms	1-(Bromomethyl)-3-fluoro-5-(trifluoromethoxy)benzene; α-Bromo-3-fluoro-5-(trifluoromethyloxy)toluene; (3-Fluoro-5-(trifluoromethoxy)phenyl)methyl bromide; 3-Fluoro-5-trifluoromethoxybenzyl bromide; 3-Fluoro-5-(trifluoromethoxy)benzylbromide; 86256-51-1; 3-Fluoro-5-(trifluoromethoxy)benzyl bromide
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Trifluoromethoxy)Benzyl Bromide, 97% is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the specified 97% minimum assay. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.