Description

1,3-Dioxolan-4-One, 5-(Chloromethyl)-2-Methyl- CAS NO 86164-33-2 is a versatile heterocyclic building block and reactive intermediate characterized by its dioxolane ring and chloromethyl functional group. This compound is valued for its bifunctional reactivity, enabling its use as a key synthon in the synthesis of complex molecules and functional materials. It is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing heterocyclic or spirocyclic motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polymers, coatings, and resins with tailored properties.
• Chemical Research & Development: An essential building block in medicinal chemistry and process chemistry for exploring new synthetic routes and lead optimization.
• Ligand & Catalyst Preparation: Utilized in the synthesis of complex ligands and organocatalysts for asymmetric synthesis and other catalytic applications.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fine chemicals and advanced intermediates for various industrial sectors.

Basic Information

Product Name	1,3-Dioxolan-4-One, 5-(Chloromethyl)-2-Methyl-
CAS No.	86164-33-2
Molecular Formula	C5H7ClO3
Molecular Weight	150.56 g/mol
Synonyms	5-(Chloromethyl)-2-methyl-1,3-dioxolan-4-one; 2-Methyl-5-(chloromethyl)-1,3-dioxolan-4-one; 4H-1,3-Dioxol-4-one, 5-(chloromethyl)-2-methyl-; (Chloromethyl)methyl dioxolone; 86164-33-2
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolan-4-One, 5-(Chloromethyl)-2-Methyl- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Chloride Content	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.