Description

(3Ar,6R,6Ar)-6-(Benzyloxymethyl)-2,2-Dimethyldihydrofuro[3,4-D][1,3]Dioxol-4(3Ah)-One is a high-purity chiral building block and protected sugar derivative of significant value in synthetic organic chemistry. Its precise stereochemistry and functional groups make it an essential intermediate for the synthesis of complex nucleoside analogs, antiviral agents, and other biologically active molecules. This compound is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in advanced medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel nucleoside-based antiviral and anticancer therapeutics.
• Nucleoside Chemistry: Serves as a protected sugar moiety for the synthesis of modified nucleosides and nucleotides with potential biological activity.
• Process Chemistry: Used in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) requiring sophisticated carbohydrate chemistry.
• Academic Research: A valuable tool for chemists studying stereoselective synthesis, glycosylation reactions, and the construction of complex heterocyclic systems.
• Fine Chemical Synthesis: Employed in the production of specialty chemicals, ligands, and catalysts where specific chirality and functionalization are critical.

Basic Information

Product Name	(3Ar,6R,6Ar)-6-(Benzyloxymethyl)-2,2-Dimethyldihydrofuro[3,4-D][1,3]Dioxol-4(3Ah)-One
CAS No.	85846-80-6
Molecular Formula	C15H18O5
Molecular Weight	278.30 g/mol
Synonyms	6-O-Benzyl-1,2-O-isopropylidene-α-D-glucofuranose-3-ulose; 3-Keto-1,2:5,6-di-O-isopropylidene-6-O-benzyl-α-D-allofuranose; 6-O-Benzyl-3-keto-1,2:5,6-di-O-isopropylidene-α-D-allofuranose; 1,2:5,6-Di-O-isopropylidene-6-O-benzyl-α-D-ribo-hexofuranos-3-ulose; Benzyl 3-keto-1,2:5,6-diisopropylidene-α-D-allofuranoside; (3R,3aR,6R,6aR)-6-(Benzyloxymethyl)-2,2-dimethyldihydrofuro[3,4-d][1,3]dioxol-4(3aH)-one
EINECS	Contact for details

Quality Control

Our (3Ar,6R,6Ar)-6-(Benzyloxymethyl)-2,2-Dimethyldihydrofuro[3,4-D][1,3]Dioxol-4(3Ah)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.