Description

2-Fluorophenyl Chlorothioformate is a specialized organosulfur reagent featuring both a chlorothioformate and a fluorinated aromatic group. This compound is valued for its dual reactivity, serving as a versatile building block for the synthesis of thiocarbamates, thiocarbonates, and other sulfur-containing heterocycles. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated phenylthio moiety.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Polymer Chemistry: Acts as a chain transfer agent or functional monomer in the production of specialty polymers with tailored properties.
• Material Science Research: Employed in surface modification and the creation of advanced organic materials.
• Chemical Biology: Useful as a probe or linker in bioconjugation strategies due to its reactive chlorothioformate group.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and fine chemical manufacturers for bespoke chemical production.

Basic Information

Product Name	2-Fluorophenyl Chlorothioformate
CAS No.	85768-50-9
Molecular Formula	C7H4ClFOS
Molecular Weight	190.62 g/mol
Synonyms	Chlorothioformic Acid O-(2-Fluorophenyl) Ester; 2-Fluorophenyl Chlorothionoformate; o-Fluorophenyl Chlorothioformate; Carbonochloridothioic Acid O-(2-Fluorophenyl) Ester; 2-Fluorophenyl Chlorosulfanylmethanoate
EINECS	Contact for details

Quality Control

Every batch of 2-Fluorophenyl Chlorothioformate is produced and tested under strict quality management protocols to ensure consistency and reliability for your synthetic workflows. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.