Description

4'-Fluoro-2-Mercapto-5-(Trifluoromethyl)Benzophenone is a high-value, multi-functional organic intermediate characterized by its unique trifluoromethyl and thiol functional groups. This compound matters for its critical role in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure imparts desirable properties like metabolic stability and lipophilicity. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand and Catalyst Precursor: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its conjugated benzophenone core.
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring fluorinated thiol chemistry.

Basic Information

Product Name	4'-Fluoro-2-Mercapto-5-(Trifluoromethyl)Benzophenone
CAS No.	85721-02-4
Molecular Formula	C14H8F4OS
Molecular Weight	300.27 g/mol
Synonyms	2-Mercapto-4'-fluoro-5-(trifluoromethyl)benzophenone; 5-(Trifluoromethyl)-2-mercapto-4'-fluorobenzophenone; 4'-Fluoro-α-oxo-5-(trifluoromethyl)benzenethiol; [4-Fluorophenyl][2-mercapto-5-(trifluoromethyl)phenyl]methanone; 85721-02-4; 4'-Fluoro-2-mercaptobenzophenone derivative
EINECS	Contact for details

Quality Control

Our 4'-Fluoro-2-Mercapto-5-(Trifluoromethyl)Benzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is easily oxidized and light-sensitive; avoid exposure to air, moisture, and direct light during handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.