Description

Cyclohexanamine, 2-Fluoro-3,5,5-Trimethyl-, (1Alpha,2Beta,3Beta)- (9Ci) is a fluorinated cyclohexylamine derivative, a specialized chiral building block of significant interest in advanced organic synthesis. Its value lies in the precise stereochemistry and the introduction of a fluorine atom, which can dramatically alter the biological activity, metabolic stability, and physicochemical properties of target molecules. This high-purity intermediate is critically needed by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances bioactivity and environmental persistence.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or modifying agent for specialty polymers with unique thermal or surface properties.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research into the structure-activity relationships (SAR) imparted by fluorinated cyclohexyl motifs.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value fine chemicals and dyes.

Basic Information

Product Name	Cyclohexanamine, 2-Fluoro-3,5,5-Trimethyl-, (1Alpha,2Beta,3Beta)- (9Ci)
CAS No.	85623-64-9
Molecular Formula	C9H18FN
Molecular Weight	159.25 g/mol
Synonyms	(1α,2β,3β)-2-Fluoro-3,5,5-trimethylcyclohexanamine; 2-Fluoro-3,5,5-trimethylcyclohexanamine (stereoisomer); (1R,2S,3S)-2-Fluoro-3,5,5-trimethylcyclohexan-1-amine; Fluorinated trimethylcyclohexylamine; F-TMCHA; 85623-64-9; Aminofluorotrimethylcyclohexane
EINECS	Contact for details

Quality Control

Every batch of Cyclohexanamine, 2-Fluoro-3,5,5-Trimethyl-, (1Alpha,2Beta,3Beta)- (9Ci) is manufactured and analyzed under a strict quality management system. We guarantee high chiral purity and chemical integrity through advanced analytical techniques including chiral HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to ensure it meets your precise research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.