Description

4-Hydroxy-3,3-Bis(Hydroxymethyl)Butyraldehyde is a versatile polyfunctional aldehyde derivative with significant utility as a key building block in organic synthesis. Its unique structure, featuring both aldehyde and multiple hydroxyl groups, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for R&D and production in industries such as pharmaceuticals, specialty polymers, and fine chemicals, where it serves as a precursor for cross-linking agents, dendrimers, and other advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs requiring complex polyol or aldehyde-based backbones.
• Polymer & Resin Chemistry: Serves as a cross-linking agent and monomer for producing specialty polymers, coatings, and resins with enhanced durability and specific functional properties.
• Dendrimer & Hyperbranched Polymer Synthesis: Acts as a core or branching unit due to its multiple reactive sites, enabling the construction of precisely defined macromolecular architectures.
• Fine Chemical Synthesis: Used in the preparation of complex organic compounds, including ligands, chelating agents, and other specialty chemicals for research and industrial applications.
• Bioconjugation & Linker Chemistry: Its aldehyde group is utilized for conjugation reactions in biotechnological applications, such as protein labeling and immobilization.
• Adhesive & Sealant Formulations: Contributes to the development of high-performance adhesives and sealants through its reactivity and ability to form stable networks.

Basic Information

Product Name	4-Hydroxy-3,3-Bis(Hydroxymethyl)Butyraldehyde
CAS No.	85586-73-8
Molecular Formula	C6H12O4
Molecular Weight	148.16 g/mol
Synonyms	3,3-Bis(hydroxymethyl)-4-hydroxybutanal; 4-Hydroxy-3,3-bis(hydroxymethyl)butanal; 2,2-Bis(hydroxymethyl)-3-hydroxypropanal; 3-Hydroxy-2,2-bis(hydroxymethyl)propanal; 2,2-Bis(hydroxymethyl)-3-hydroxypropionaldehyde; 3,3-Di(hydroxymethyl)-4-hydroxybutyraldehyde; 4-Hydroxy-3,3-dimethylolbutyraldehyde; Tris(hydroxymethyl)acetaldehyde hydrate (related form)
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3,3-Bis(Hydroxymethyl)Butyraldehyde is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.