Description

2-Chloro-1-(Pyridin-2-Yl)Ethanone Hydrochloride is a versatile and reactive organic salt, primarily serving as a key synthetic intermediate in advanced pharmaceutical and agrochemical research. Its value lies in its pyridine and α-chloro ketone functional groups, which enable the construction of complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new molecules and optimize synthetic routes.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those containing pyridine or piperidine motifs.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides.
• Chemical Research & Development: Serves as a versatile reagent for constructing complex heterocyclic compounds in academic and industrial laboratories.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the production scale-up of specific APIs requiring its unique molecular scaffold.
• Ligand and Catalyst Precursor: Useful in the preparation of specialized ligands for metal-catalyzed reactions.

Basic Information

Product Name	2-Chloro-1-(Pyridin-2-Yl)Ethanone Hydrochloride
CAS No.	85577-69-1
Molecular Formula	C7H7Cl2NO
Molecular Weight	192.04 g/mol
Synonyms	2-Chloro-1-(2-pyridinyl)ethanone hydrochloride; 2-Acetylpyridine hydrochloride, 2-chloro-; 2-Pyridyl chloromethyl ketone hydrochloride; α-Chloro-2-pyridyl methyl ketone hydrochloride; 1-(2-Pyridinyl)-2-chloroethanone hydrochloride; 2-Chloro-1-pyridin-2-ylethanone hydrochloride; 85577-69-1; Ethanone, 2-chloro-1-(2-pyridinyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(Pyridin-2-Yl)Ethanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.