Description

1H-1,2,4-Triazole,1-[(Butyldimethylsilyl)Methyl]-(9Ci) is a specialized organosilicon-protected triazole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its dual functionality, offering both the reactive triazole heterocycle and a robust silyl protecting group, which is essential for multi-step synthetic sequences. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecules, particularly in nucleoside and nucleotide chemistry.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer agents, especially those containing modified nucleoside analogs.
• Agrochemical Synthesis: Used in the development of new generation fungicides and herbicides that leverage the triazole pharmacophore.
• Organometallic Catalyst Ligand: Acts as a ligand precursor for transition metal catalysts used in cross-coupling and other catalytic transformations.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored thermal and chemical properties.
• Chemical Biology Probe Development: Utilized in the synthesis of activity-based probes and bioconjugation reagents for studying enzymatic processes.
• Material Science Research: Building block for creating silicon-containing advanced materials, such as silsesquioxanes and other hybrid organic-inorganic frameworks.

Basic Information

Product Name	1H-1,2,4-Triazole,1-[(Butyldimethylsilyl)Methyl]-(9Ci)
CAS No.	85491-48-1
Molecular Formula	C8H19N3Si
Molecular Weight	185.34 g/mol
Synonyms	1-[(Butyldimethylsilyl)methyl]-1H-1,2,4-triazole; 1-(Butyldimethylsilylmethyl)-1,2,4-triazole; N-[(Butyldimethylsilyl)methyl]-1,2,4-triazole; 1-(Butyldimethylsilylmethyl)-1H-1,2,4-triazole; (Butyldimethylsilyl)methyltriazole; BDMST; 1,2,4-Triazole, 1-[(butyldimethylsilyl)methyl]- (9CI)
EINECS	Contact for details

Quality Control

Our 1-[(Butyldimethylsilyl)methyl]-1H-1,2,4-triazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality supports applications requiring reliable and reproducible synthetic building blocks for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.