Description

1-Propanone, 2-Chloro-1-Phenyl-, (2S)- (9Ci) is a chiral, optically active organic compound featuring a phenyl ketone structure with a chlorine substituent. This specific stereochemistry makes it a valuable chiral building block and intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research and development chemists and process development scientists for the production of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates, especially for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric catalysis.
• Fine Chemical Production: Employed in the manufacture of specialty and performance chemicals requiring high enantiomeric purity.
• Academic and Industrial Research: A valuable reference standard and starting material in organic chemistry research focused on stereoselective reactions.

Basic Information

Product Name	1-Propanone, 2-Chloro-1-Phenyl-, (2S)- (9Ci)
CAS No.	85439-24-3
Molecular Formula	C9H9ClO
Molecular Weight	168.62 g/mol
Synonyms	(S)-2-Chloro-1-phenylpropan-1-one; (S)-2-Chloropropiophenone; (2S)-2-Chloro-1-phenyl-1-propanone; (S)-α-Chloropropiophenone; (S)-2-Chloro-1-phenylpropanone; (S)-Phenyl 2-chloropropyl ketone; (S)-1-Phenyl-2-chloropropan-1-one; (S)-2-Chloro-1-phenyl-1-propanone
EINECS	Contact for details

Quality Control

Our chiral intermediates are produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot of (S)-2-Chloro-1-phenylpropan-1-one is characterized by advanced analytical techniques including chiral HPLC, GC, and NMR to confirm identity, chemical purity, and enantiomeric excess (ee). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.