Description

1,2-Epoxy-3-(4'-Azido-2'-Nitrophenoxy)Propane is a specialized bifunctional chemical building block that combines an epoxy group with an aromatic azide moiety. This unique structure makes it a critical reagent for photoaffinity labeling and cross-linking studies in biochemistry and materials science. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and advanced polymer sectors for developing targeted probes and functional materials.

Application

• Photoaffinity Labeling Probes: Acts as a key intermediate for synthesizing probes to study protein-ligand interactions and binding sites.
• Bioconjugation & Cross-linking: Used to create covalent links between biomolecules (e.g., proteins, nucleic acids) and other surfaces or molecules under controlled light activation.
• Polymer Functionalization: Serves as a monomer or cross-linker for introducing photoreactive azide groups into polymer backbones for specialty coatings and adhesives.
• Surface Modification: Enables the photochemical grafting of functional layers onto various substrates for biosensor and diagnostic device development.
• Materials Science Research: Employed in the development of light-responsive "smart" materials and hydrogels.
• Chemical Biology Tool Development: A foundational compound for creating novel reagents that allow for the spatial and temporal control of chemical reactions in complex biological systems.

Basic Information

Product Name	1,2-Epoxy-3-(4'-Azido-2'-Nitrophenoxy)Propane
CAS No.	85416-40-6
Molecular Formula	C9H8N4O4
Molecular Weight	236.18 g/mol
Synonyms	4-Azido-2-nitrophenyl glycidyl ether; 2-Nitro-4-azidophenyl glycidyl ether; Glycidyl 4-azido-2-nitrophenyl ether; ANP-GE; 1,2-Epoxy-3-((4-azido-2-nitrophenyl)oxy)propane; 3-(4-Azido-2-nitrophenoxy)-1,2-epoxypropane; NAP-glycidyl ether
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with research-grade standards. Identity and purity are verified using advanced analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your critical R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) for long-term stability. Due to the presence of both azide and epoxy functional groups, this compound should be handled with appropriate precautions and stored separately from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (e.g., DMSO, acetone, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.