Description

Ethanone, 2-Chloro-1-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-, (R)- (9Ci) CAS NO 85364-10-9 is a high-purity chiral building block, specifically the (R)-enantiomer of a protected chloroacetyl derivative. This compound is a critical intermediate in the synthesis of complex pharmaceutical molecules, offering precise stereochemical control for the development of active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the production of chiral drugs and advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure APIs, particularly in antiviral, anticancer, and cardiovascular drug research.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to introduce the (R)-configured chloroacetyl moiety into target molecules.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial R&D: Employed in method development and process chemistry research for novel synthetic pathways.
• Agrochemical Synthesis: Potential intermediate in the development of chiral pesticides and herbicides.

Basic Information

Product Name	Ethanone, 2-Chloro-1-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-, (R)- (9Ci)
CAS No.	85364-10-9
Molecular Formula	C7H11ClO3
Molecular Weight	178.62 g/mol
Synonyms	(R)-2-Chloro-1-(2,2-dimethyl-1,3-dioxolan-4-yl)ethanone; (4R)-2-Chloro-1-(2,2-dimethyl-1,3-dioxolan-4-yl)ethanone; (R)-(-)-2-Chloro-1-(2,2-dimethyl-1,3-dioxolan-4-yl)ethanone; (R)-2-Chloro-1-(2,2-dimethyl-1,3-dioxolan-4-yl)ethan-1-one; 2-Chloro-1-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]ethanone; Acetone, 2-chloro-1-(2,2-dimethyl-1,3-dioxolan-4-yl)-, (R)-; (R)-2-Chloro-1-(2,2-dimethyl-[1,3]dioxolan-4-yl)-ethanone
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Chloro-1-(2,2-Dimethyl-1,3-Dioxolan-4-Yl)-, (R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) determination by HPLC, identity confirmation by IR and NMR spectroscopy, and impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.