Description

(1R,2S)-Indene Oxide is a high-purity chiral epoxide derived from indene, serving as a critical chiral building block in advanced organic synthesis. Its defined stereochemistry is essential for imparting specific three-dimensional structure and biological activity to target molecules. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical industries developing enantiomerically pure active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Asymmetric Catalysis Research: Employed as a standard substrate or ligand precursor in the development and testing of new chiral catalysts and methodologies.
• Fine Chemical Production: Serves as a starting material for the manufacture of complex fragrances, flavors, and other specialty chemicals requiring precise stereocontrol.
• Material Science: Potential monomer or cross-linking agent in the synthesis of polymers with specific optical or structural properties.

Basic Information

Product Name	(1R,2S)-Indene Oxide
CAS No.	85354-35-4
Molecular Formula	C9H8O
Molecular Weight	132.16 g/mol
Synonyms	(1R,2S)-1,2-Epoxyindane; (-)-(1R,2S)-Indene Oxide; (1R,2S)-1,2-Dihydro-1,2-epoxynaphthalene; (1R,2S)-Indane-1,2-oxide; (1R-cis)-1,2-Epoxyindane; Indene oxide, (1R,2S)-(-)-; (-)-cis-1,2-Epoxyindane
EINECS	Contact for details

Quality Control

Our (1R,2S)-Indene Oxide is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.