Description

1-Propanone, 2-Chloro-1-(4-Methoxyphenyl)-, (R)- (9Ci) is a chiral, non-racemic organic compound featuring a chlorinated propanone backbone substituted with a methoxyphenyl group. This compound matters as a valuable chiral building block and synthetic intermediate, enabling the stereoselective construction of more complex molecules. It is needed by researchers and process chemists in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly where stereochemistry is critical for biological activity.
• Asymmetric Synthesis: Used as a starting material or reagent in stereoselective organic reactions, including aldol condensations and nucleophilic substitutions.
• Fine Chemical Production: Serves as a precursor in the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials.
• Academic & Industrial Research: Employed in methodological studies and process chemistry for exploring new catalytic pathways and synthetic routes.
• Ligand and Catalyst Development: Can be utilized in the synthesis of chiral ligands or organocatalysts for enantioselective transformations.

Basic Information

Item	Details
Product Name	1-Propanone, 2-Chloro-1-(4-Methoxyphenyl)-, (R)- (9Ci)
CAS No.	85277-58-3
Molecular Formula	C10H11ClO2
Molecular Weight	198.65 g/mol
Synonyms	(R)-2-Chloro-1-(4-methoxyphenyl)propan-1-one; (R)-2-Chloro-1-(4-methoxyphenyl)propanone; (R)-2-Chloro-4'-methoxypropiophenone; (R)-α-Chloro-4-methoxypropiophenone; (R)-1-(4-Methoxyphenyl)-2-chloropropan-1-one; (R)-p-Methoxy-α-chloropropiophenone; (R)-85277-58-3; (R)-Enantiomer of 2-Chloro-1-(4-methoxyphenyl)propan-1-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support research and development needs. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request for every batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere if frequent access is not required. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.