Description

(2S,4Aα,8Aβ)-3,4,4A,5,6,7,8,8A-Octahydro-2,7β-Dihydroxy-4α-(3-Hydroxy-1-Oxopropyl)-2,4β,5α,7α-Tetramethyl-3α-[(R)-1-Methylpropyl]-1(2H)-Naphthalenone is a complex, high-purity synthetic intermediate with a defined stereochemistry that is critical for advanced organic synthesis. Its value lies in its role as a key chiral building block for the development of novel pharmaceutical compounds and fine chemicals. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate sophisticated polycyclic structures into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for steroids and other polycyclic therapeutic agents.
• Agrochemical Research: Used as a chiral synthon in the development of new generation pesticides and herbicides with enhanced specificity and activity.
• Fine Chemical Synthesis: Employed in advanced organic chemistry for constructing intricate molecular architectures found in fragrances, flavors, and specialty materials.
• Academic & Industrial R&D: A valuable compound for methodological studies in asymmetric synthesis, catalysis, and total synthesis projects.
• Process Chemistry Development: Utilized for scaling up synthetic routes and optimizing production processes for complex molecules in pilot plants.

Basic Information

Product Name	(2S,4Aα,8Aβ)-3,4,4A,5,6,7,8,8A-Octahydro-2,7β-Dihydroxy-4α-(3-Hydroxy-1-Oxopropyl)-2,4β,5α,7α-Tetramethyl-3α-[(R)-1-Methylpropyl]-1(2H)-Naphthalenone
CAS No.	85269-23-4
Molecular Formula	C22H38O5
Molecular Weight	382.54 g/mol
Synonyms	3,4,4a,5,6,7,8,8a-Octahydro-2,7-dihydroxy-4a-(3-hydroxy-1-oxopropyl)-2,4b,5,7a-tetramethyl-3a-[(1R)-1-methylpropyl]-1(2H)-naphthalenone; (2S,4aR,8aS)-2,7-Dihydroxy-4a-[(R)-3-hydroxybutanoyl]-2,4b,5,7a-tetramethyl-3a-pentyl-3,4,4a,5,6,7,8,8a-octahydro-1H-naphthalen-1-one; 85269-23-4; A key chiral naphthalenone derivative.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We employ state-of-the-art analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture uptake, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.