Description

Methyl α-Bromo-2-Chlorophenylacetate is a specialized halogenated ester building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals, where its reactive bromine and ester functionalities enable key carbon-carbon bond-forming reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging its halogenated aromatic structure.
• Fine Chemical Manufacturing: Serves as a versatile building block for creating complex esters, acids, and other derivatives in custom synthesis.
• Research & Development: Employed in academic and industrial R&D for method development and exploring new synthetic pathways.
• Peptide Mimetics: Utilized in the construction of peptide analogs and enzyme inhibitors due to its α-bromo functionality.

Basic Information

Product Name	Methyl α-Bromo-2-Chlorophenylacetate
CAS No.	85259-19-4
Molecular Formula	C9H8BrClO2
Molecular Weight	263.52 g/mol
Synonyms	Methyl 2-Bromo-2-(2-chlorophenyl)acetate; Methyl α-Bromo-o-chlorophenylacetate; 2-Bromo-2-(2-chlorophenyl)acetic Acid Methyl Ester; (2-Chlorophenyl)(bromo)acetic Acid Methyl Ester; Methyl (2-Bromo-2-(2-chlorophenyl)acetate); α-Bromo-2-chlorophenylacetic acid methyl ester; NSC 402284; Methyl bromo(2-chlorophenyl)acetate
EINECS	Contact for details

Quality Control

Our production of Methyl α-Bromo-2-Chlorophenylacetate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.