Description

(1S,2S,3R,5S)-(+)-2,3-Pinanediol Butylboronate Ester is a high-purity, chiral boronic ester derivative of pinanediol, serving as a crucial chiral auxiliary and reagent in asymmetric synthesis. Its primary value lies in enabling highly stereoselective transformations, particularly in the synthesis of complex pharmaceutical intermediates and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, enantiomerically pure building blocks.

Application

• As a chiral derivatizing agent for the analysis and separation of enantiomers via chromatography or spectroscopy.
• Key intermediate in the asymmetric synthesis of bioactive molecules, including active pharmaceutical ingredients (APIs).
• Utilized in Suzuki-Miyaura cross-coupling reactions to introduce chiral boronate moieties under mild conditions.
• Employed as a temporary protecting group for diols in multi-step synthetic sequences.
• Precursor for the preparation of other chiral organoboron compounds used in catalysis and material science.
• Research and development of novel chiral ligands and catalysts for industrial-scale asymmetric processes.

Basic Information

Product Name	(1S,2S,3R,5S)-(+)-2,3-Pinanediol Butylboronate Ester
CAS No.	85167-10-8
Molecular Formula	C₁₄H₂₅BO₂
Molecular Weight	236.16 g/mol
Synonyms	(+)-Pinanediol Butylboronate; (1S,2S,3R,5S)-(+)-Pinanediol n-Butylboronate; Butylboronic Acid Pinanediol Ester; (1S,2S,3R,5S)-Pinane-2,3-diol Butylboronate; n-Butylboronic Acid Pinanediol Ester; B-Butyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (related structural analog); Butylboronate Pinanediol Ester
EINECS	Contact for details

Quality Control

Our (1S,2S,3R,5S)-(+)-2,3-Pinanediol Butylboronate Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting research and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to maintain stability and prevent hydrolysis or oxidation. The container should be kept tightly sealed in a desiccated environment due to its hygroscopic nature.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.